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These cut‐offs, based on a reference population at low risk of subclinical liver disease, were originally suggested by Prati et al.34 Changes in ALT from baseline were analysed by baseline ALT subgroup using a mixed model for repeated measurements with log‐transformed baseline ALT as the covariate, and with treatment, sex and either region (weight management trial) or stratification (cardiovascular outcomes trial

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Timeline: When Diarrhea Typically Starts and Resolves Many people notice loose stools within the first 3-7 days after their initial injection or first dose